Because the OATP variant has poor transport capacity compared to the lt-OATP1B3, paclitaxel uptake by ct-OATP1B3 into ovarian cancer cells is unlikely (Thakkar et al., 2013; Sun et al., 2014; Furihata et al., 2015; Sissung et al., 2017; Alam et al., 2018). The gene discussed is SLCO1B3; the disease is ovarian cancer.