DUSP22 and schizophrenia: In contrast, the schizophrenia patients had significantly lower DUSP22 transcript levels (schizophrenia: N = 60, DUSP22 expression = 2.97, sd = 0.17; controls: N = 96, DUSP22 expression = 2.87, sd = 0.21) (B = −0.09, p = 0.005), also after adjustment for genetic background (B = −0.14, p < 0.001), suggesting transcriptional regulation of DUSP22 by other factors than DNA methylation in the adult brain of schizophrenia patients.