After 6 months of follow-up, continence was not affected and both patients presented with PSA < 0.15 ng / mL.<h4>Conclusion</h4>Robot - assisted laparoscopic resection of prostate cancer local recurrence after RP and sRDT detected by PSMA PET / CT seems to be safe in experienced hands. This evidence concerns the gene FOLH1 and Familial prostate cancer.