IFNA1 and influenza: First, S. aureus, another common coinfecting bacteria, was shown to inhibit IFN signaling in influenza‐infected cells, which resulted in increased virus production.125 Although it is unknown if pneumococci have this same ability and to what extent this occurs in vivo, particularly considering the enhanced IFN levels during coinfection,86, 87, 88 it is an intriguing finding and validates the model‐generated hypothesis.