The single ion images of the two sphingolipids that we had identified as PB classifiers, namely HexCer(t36:2) [m/z 742.5824 (AUCmax = 0.04)] and CerP(d47:2) [m/z 836.6292 (AUCmax = 0.06)], revealed high signal intensity that was present homogeneously throughout dense tumor regions of PB tissue sections. Here, ABCA1 is linked to neoplasm.