Further research has supported such findings: CTCF is mutated in a subset of individuals with intellectual disabilities (Gregor et al., 2013) and its binding partners such as cohesion (Wendt et al., 2008), CHD8 (Ishihara et al., 2006; O’Roak et al., 2012), and MeCP2 (Kernohan et al., 2014) have been implicated in neurodevelopmental disorders. This evidence concerns the gene CTCF and neurodevelopmental disorder.