S100A4 and pulmonary fibrosis: The anti-S100A4 alone had no effect on the lung tissues of WT mice while bleomycin-induced pulmonary fibrosis with strong immune-cell infiltration and alveolar destruction as well as collagen deposition, simultaneous anti-S100A4 nicely prevented all signs of bleomycin-induced pulmonary fibrosis (Figures 5G,H).