Very recently, Kaur et al. have shown that a recombinant fragment of human SP-D, composed of homotrimeric neck and C-type lectin domains, can induce apoptosis in pancreatic adenocarcinoma cell lines, such as Panc-1 (p53mt), MiaPaCa-2 (p53mt), and Capan-2 (p53wt), via Fas-mediated pathway (20). This evidence concerns the gene FAS and pancreatic adenocarcinoma.