The crossover between the respective mechanisms by which cisplatin and motion induce emesis via hypothalamic, vestibular and medullary pathways interests us the most when we attempt to understand the anti-emetic mechanisms of action of HM01, because GHS-R1A is distributed in these brain areas (Bron et al., 2013) and because a history of motion sickness is a risk factor for chemotherapy-induced nausea and emesis in humans (Hesketh, 2008). This evidence concerns the gene GHSR and Nausea and vomiting.