CASP3 and neoplasm: Increases Caspase-3 expression and translocation of phosphatidylserine in lectin-treated colon26 cells, suggesting that cell death is mediated by apoptosis. In vivo is observed a significant growth inhibition of Colon26-induced tumors on BALB/c mice. DNA fragmentation in tumor cells after intravenous injection with ESA is also detected.