BCL11A and neoplasm: To investigate if BCL11A is required for SOX2-mediated oncogenesis we introduced a doxycycline inducible BCL11A overexpression vector into SOX2-KD cell lines and found that BCL11A overexpression partially rescues the colony and tumour formation abilities of SOX2-KD cells (Fig. 3e–h, and Supplementary Fig. 8a–c).