In the multivariate regression analysis adjusted for age, gender, fasting blood sugar (FBS), baseline eGFR, hemoglobin, LVEF, contrast volume, and peri-procedure N-acetylcysteine (NAC) usage, serum FGF21 remained independently associated with the incidence of CIN (adjusted odds ratio, 4.66; 95% CI, 1.29–16.86; p = 0.019; Table 3). The gene discussed is FGF21; the disease is cervical squamous intraepithelial neoplasia.