VCP and amyotrophic lateral sclerosis: Intriguingly, genes associated with ALS encode for proteins involved in autophagy, mitophagy, and proteostasis, including TBK1 (tank‐binding kinase 1), and VCP (valosin‐containing protein or p97; Johnson et al, 2010; Freischmidt et al, 2015), suggesting that MQC participates in disease pathogenesis.