In total, we analyzed the levels of three NPM1 transcripts, NPM1.1, NPM1.2 and NPM1.3, in 66 mononuclear cell samples (extracted from peripheral blood, PB, or bone marrow, BM) collected at the time of the first diagnosis from adult patients with acute leukemia and from 16 adult healthy volunteers (HV). Here, NPM1 is linked to acute leukemia.