Basically, at the time of diagnosis, the cohort mean (SD) age was 68.6 (8.72) years, The baseline PSA was ≤10 ng/mL in 948 (66.5%) patients, 566 (39.7%) patients had a Gleason score of ≤6 and 477 (33.4%) patients were classified as having low risk PCa according to D’Amico risk classification criteria. Here, KLK3 is linked to posterior cortical atrophy.