Moreover, despite the limitation that the expression of Ox-PTP was evaluated by semi-quantitative immunohistochemical staining which does not delineate the type of PTPs oxidized in gastric cancers, to our knowledge this is the first study to evaluate oxidized PTPs in human cancer tissue and to elucidate their potential as a prognostic marker of gastric carcinomas. The gene discussed is PTS; the disease is gastric cancer.