Although the incidence of pathogenic mutations was lower than our assumptions at the beginning of the study, we established the method for the molecular analysis of INF2 and analyzed a large cohort of patients with FSGS/MCD; confirming that MCD cases are less likely to harbor deleterious genetic variants in those genes implicated in FSGS [4–6, 19]. Here, INF2 is linked to focal segmental glomerulosclerosis.