Postoperative CTC count changes were not significantly associated with age, sex, hepatitis B viral (HBV) infection, liver cirrhosis, Child-Pugh score, AFP, tumor size, tumor number, vascular invasion, BCLC stage, mode of operation (open or laparoscopic), operation duration, blood loss, blood transfusion or hepatic vascular occlusion during the operation. This evidence concerns the gene AFP and neoplasm.