NEK2 was altered in 22.9% of analyzed tumor samples and found interacted with the α-tubulin isoforms TUBA1A, TUBA4A, the β-tubulin isoforms TUBB, TUBB4A, TUBB4B and all the γ-tubulin isoforms (Figure 1C). This evidence concerns the gene TUBB4B and neoplasm.