CXCL8 and cancer: CXCL8/IL8 expression has been detected across several cancer indications [79] including both solid [80,81,82,83,84,85,86] and haematological malignancies [79,87,88] and thus, one might speculate, whether CXCR2 transduction might not be as efficient in these malignancies as the CCR2 and CCR4 proposed above.