CDKN2A and supranuclear palsy, progressive, 1: Consistent with the results from transgenic mice, CDKN2A was upregulated in PSP brains (p = 0.0415, Figure 4g) and expression correlated with NFT deposition, specifically in the parietal lobe (ANOVA, p = 0.0008; Kendall's Tau rank correlation, p = 0.059, Figure 4h).