CD4 and tuberculosis: In a prospective observational study of 170 TB patients with CD4 counts less than 125 cells/μl, starting ART in Botswana, 33 (19%) patients developed paradoxical TB-IRIS and 18 (11%) patients died, but there was only one (3%) death among TB-IRIS patients, reported as occurring after the resolution of TB-IRIS symptoms [17].