In addition,Ramachandran and Bell reported that there were nosignificant differences in genotype frequencies betweenMS patients and controls in either HSP70-2 or HSP70hom,and the gene polymorphisms of HSP70-2 andHSP70- hom did not increase susceptibility to MS (21).Cascino et al. (22) reported no significant differencebetween the MS patient group and the control groupin the promoter region polymorphism of HSP70-1.In contrast, a study has shown that a HSP70-2 genepolymorphism and HSP70-2 protein level expression aresignificantly associated in Italian MS patients (23). Here, HSPA1A is linked to myeloid sarcoma.