The primary target of HTLV‐1 is CD4+ T‐cells; however, there is evidence for infection of a range of immune cells including DC (Knight, Macatonia, Cruickshank, Rudge, & Patterson, 1993; Macatonia, Cruickshank, Rudge, & Knight, 1992), macrophages (Nath, Ruscetti, Petrow‐Sadowski, & Jones, 2003), B‐cells (Koyanagi et al., 1993), and CD8+ T‐cells (Hanon et al., 2000). Here, CD4 is linked to infection.