In ERA patients (Study population-1), Chemerin but not PEDF plasma values positively correlated with disease activity scores (DAS: R = 0.33; p < 0.001; SDAI: R = 0.30; p < 0.001) and disability index (HAQ: R = 0.21; p = 0.01) (Supplemental Table 1 and Figure 1D). This evidence concerns the gene RARRES2 and enthesitis-related juvenile idiopathic arthritis.