Focusing on the defense response to bacteria, which Centrality increased by 53,000-fold in response to infection, the proteins driving this change were the ras-related proteins Rab14 (B7QHS7 and L7M7N3) over-represented in ItC, and the antimicrobial peptide microplusin (Q09JR4) that was represented only in ItC (Supplementary Table 2). Here, RASD1 is linked to infection.