In our former study (Zhang et al. 2011), we reported that 11ʹ-deoxyverticillin A (C42), a member of a class of fungal secondary metabolites known as epipolythiodioxopiperazines (ETPs), could induce autophagy and necrotic cell death of tumour cells through RIP1. The gene discussed is RIPK1; the disease is neoplasm.