The meta-analysis results of these studies showed that there were no significant differences in the above motor phenotypes in the LRRK2 G2385R-carrier PD group compared to LRRK2 G2385R-noncarrier PD group (tremor: OR = 0.88, 95% CI: 0.40−1.91, P=0.74, Supplementary Figure 7A; rigidity: OR = 1.59, 95% CI: 0.48−5.27, P=0.45, Supplementary Figure 7B; bradykinesia: OR = 0.43, 95% CI: 0.15−1.24, P=0.12, Supplementary Figure 7C; PIGD: OR = 1.24, 95% CI: 0.48−3.23, P=0.66, Supplementary Figure 7D). This evidence concerns the gene LRRK2 and Parkinson disease.