LRRK2 and Parkinson disease: Five studies assessed the relationship between LRRK2 G2385R status and family history of PD, and the data showed that a family history of PD was significantly more common in the LRRK2 G2385R carriers than in the LRRK2 G2385R noncarriers (OR: 1.98; 95% CI: 1.16−3.39; P=0.01) (Supplementary Figure 1).