LRRK2 and Parkinson disease: The meta-analysis results of these studies showed no significant differences for LED, motor fluctuation, or dyskinesia between the LRRK2 G2385R-carrier PD group and the LRRK2 G2385R-noncarrier PD group (LED: MD = 0.14, 95% CI: −0.06 to 0.33, P=0.17, Supplementary Figure 9A; motor fluctuation: OR = 1.73, 95% CI: 0.99−3.01, P=0.05, Supplementary Figure 9B; dyskinesia: OR = 1.26, 95% CI: 0.63−2.54, P=0.52, Supplementary Figure 9C).