Recently, a study showed that rs11942223 was not associated with tophi in people with gout in New Zealander populations [73].In addition, the SNP rs13124007 at the promoter region was associated with gout in a Chinese male cohort [74], and its C to G substitution led to a loss of a binding site for interferon regulatory factor 1 (IRF-1) [74]. The gene discussed is IRF1; the disease is gout.