Besides, compared with cells treated with Rituximab-MMAE alone, cells treated with Rituximab-MMAE and rapamycin showed the increased cleavage of caspase 9 and PARP (Figures 5G,H; Figure S6D in Supplementary Material), while inhibition of apoptosis had no influence on the autophagy level in Rituximab-MMAE-treated NHL cells (Figure S9 in Supplementary Material). The gene discussed is CASP9; the disease is non-Hodgkin lymphoma.