In stage 2, the rs3806933T allele of TSLP, rs6897932T allele of IL7R, and g.19646A>GA allele of TSLPR also conferred significant risk for CAD (rs3806933T in TSLP, Padj = 7.51 × 10−4, OR = 1.30, 95%CI: 1.11–1.50; rs6897932T in IL7R, Padj = 5.13 × 10−4, OR = 1.40, 95%CI: 1.16–1.69; g.19646A>GA in TSLPR, Padj = 1.52 × 10−2, OR = 1.19, 95%CI: 1.03–1.36) in the validation cohort, which passed Bonferroni correction. The gene discussed is IL7R; the disease is coronary artery disorder.