Studies have shown that stimulating the neutrophil surface of CXCR1 can lead to neutrophil chemotaxis and activation (Ocana et al., 2017; Tavares et al., 2017), and inhibition of CXCR1 and CXCR2 can reduce the migration of neutrophils to tumor regions (Tavares et al., 2017). Here, CXCR1 is linked to neoplasm.