SMARCA4 and rhabdoid tumor predisposition syndrome 2: Germline truncating SMARCA4 mutations cause a very rare tumor predisposition syndrome called Rhabdoid Tumor Predisposition Syndrome 2 (RTPS2; OMIM 613325), which is characterized by the early occurrence of small-cell carcinomas of the ovary hypercalcemic type (SCCOHT) or rhabdoid brain tumors.