The treatment of Jurkat and THP-1 cells with mimics derived from oeu-sR sequences induced a significant decrease of BCL2-positive cells compared with the HF control (Fig. 3C); this event was associated with a significant increase in the pro-apoptotic BAX protein level, as assessed via western blot analysis (Fig. 3D,E). This evidence concerns the gene BCL2 and hydrops fetalis.