The sensitivity of SUZ12 and RbAp46 in ERMS was 72.55% and 68.63%, respectively, and the specificity was 93.33% and 86.67% respectively, which illustrated that SUZ12 and RbAp46 were highly specific to RMS and they may become supplementary indicators together with EZH2 for differentiating RMS from rhabdomyoma. The gene discussed is RBBP7; the disease is rhabdomyoma.