In a genome-wide expression study on kidney diseases21 accessed through the NephroSeq data base22, ADAM29 was expressed at low levels both in kidney glomeruli and tubuli; moderate under-expression of ADAM29 was detected in glomeruli of individuals with other kidney diseases (Focal Segmental Glomerulosclerosis, N = 25, p = 1.2 × 10−4; lupus nephritis, N = 32, p = 1.7 × 10−4, gene rank top 8% for both analyses). Here, ADAM29 is linked to focal segmental glomerulosclerosis.