LGALS3 and B-cell non-Hodgkin lymphoma: From the band’s apparent molecular weight (~260 kDa), we hypothesized the band was CD45, which is expressed as a full-length isoform in B cells (CD45RABC or CD45R), is known to be heavily glycosylated, and has previously been reported to bind Gal-3 in B cell lymphoma cell lines27.