S100A4 and familial pancreatic carcinoma: In the context of pancreatic cancer, lineage tracing studies revealed fibroblast‐specific protein‐1 (Fsp1, also called S100A4), Zeb1, and Snail‐expressing cancer cells, defined as cancer cells exhibiting a partial EMT program, were observed early in tumor formation (Rhim et al, 2012).