TGFB1 and kidney disorder: TGF-β islargely involved in the development of interstitial fibrosis and progression ofchronic kidney disease.24,26,31-32 As reported, it is related to the EMTprocess.20-23 Kidney macrophage influx14 and TGF-β expression after IR procedure arereduced by previous treatment with both BN doses of 75 and 150 mg.