PDGFRA and neoplasm: We previously published a kindred bearing a germline mutation (CC→TT at 1957‐58) that led to a Leu for Pro substitution at 653 (P653L) in PDGFRA gene.9 The proband featured GI tumours encompassing GISTs, IFPs (including tumours previously described as “fibrous tumours”26) and a lipoma, and an intramural diffuse stromal cell proliferation, heavily affecting the submucosa, in the stomach and proximal duodenum.