AKT1 and acute myeloid leukemia: The reprogramming of energetic metabolism in tumour cells is mainly driven by the deregulation of the nutrient‐sensing pathways.14 The occurrence of mTORC1 constitutive activation independent of PI3K/AKT and the additional possibility of AMPK activation illustrates the complexity of the interactions between the nutrient‐sensing pathways in the AML context (reviewed in Ref15, 37).