Indeed, previous studies have shown that HOTAIRM1 plays key roles in myeloid differentiation by cis‐regulating the expression of neighbouring homeobox transcription factor A (HOXA) genes.30 Thus, it is possible for H3K4me3‐activated HOTAIRM1 to contribute to the development of GBM by enhancing the expression of neighbouring HOXA1, an oncogene present in several cancers. The gene discussed is HOTAIRM1; the disease is cancer.