Mechanistic studies revealed that miR‐152 mediates the tumour‐suppressive effects of XIST silencing on GSCs, probably by direct interaction.71 Linc‐POU3F3 is one of the few lncRNAs with evolutionarily conserved sequence and genomic location, and its expression is negatively correlated with its neighbouring gene, POU3F3.72 As a TF, POU3F3 is involved in the regulation of key genes in the neurogenic differentiation of stem cells (DELTA1 and SOX2) and is required for maintaining the undifferentiated phenotype of neural precursors.73 This evidence concerns the gene SOX2 and neoplasm.