NEAT1 and glioma: NEAT1 is essential for nuclear paraspeckle formation and is overexpressed in most solid tumours.56 The expression of NEAT1 is closely correlated with higher WHO grade and recurrence in gliomas.31 Oncogenic NEAT1 depletion through the dual‐CRISPR/Cas9 system inhibited GBM cell growth and invasion both in vitro and in vivo.