Indeed, previous studies have shown that HOTAIRM1 plays key roles in myeloid differentiation by cis‐regulating the expression of neighbouring homeobox transcription factor A (HOXA) genes.30 Thus, it is possible for H3K4me3‐activated HOTAIRM1 to contribute to the development of GBM by enhancing the expression of neighbouring HOXA1, an oncogene present in several cancers. This evidence concerns the gene HOTAIRM1 and glioblastoma.