A previous study revealed that the presence of CE was associated with IDH mutation in glioblastomas.24 In another study, it was found that CE could be associated with several proangiogenic and edema‐related genes, including neuronal pentraxin‐2 and vascular endothelial growth factor in GBM patients.25 These studies increased the impetus for an integrative analysis of radiological presentation and multi‐omics data. The gene discussed is VEGFA; the disease is cholesteryl ester measurement.