Currently, with respect to HCC, a number of TAAs have been identified: α-fetoprotein (AFP), New York esophageal squamous cell carcinoma-1 (NY-ESO-1), melanoma antigen gene (MAGE) family, glypican-3 (GPC3), and so on [17]. This evidence concerns the gene GPC3 and esophageal squamous cell carcinoma.