FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: Different data indicate the relevant role of these CD4+Foxp3+ Treg cells in the pathogenesis of autoimmune diseases, including the congenital deficiency of Foxp3, which results in the IPEX syndrome (immune dysregulation, autoimmune polyendocrinopathy, and inflammatory enteropathy) [7].