Since a faster absorption from the abdomen results in a higher and faster onset of Cmax compared to insulin injected into the thigh and vice versa [67, 122, 125, 132], the abdominal region is often the preferred site for the administration of prandial insulin as it more effectively reduces postprandial hyperglycaemia compared to, for example, the thigh [130]. Here, INS is linked to Hyperglycemia.