The 1639 genes targeted by the 7 miRNAs in SDVonly are significantly enriched (raw p value < 0.05) in 6 KEGG pathways (calcium signaling pathway, salivary secretion, amyotrophic lateral sclerosis (ALS), MAPK signaling pathway, PPAR signaling pathway, and Alzheimer's disease) (Table A6). This evidence concerns the gene PPARA and Alzheimer disease.