The constantly updated human proteinreference databases are another solution to the problem of searching for anantigen that targets healthy cells [66].MHC can also be a promising antigen that discriminates between healthy cellsand tumor ones: it is expressed on the surface of almost all healthy cells,while MHC expression in cancer cells is downregulated to suppress the immuneresponse [67]. The gene discussed is HLA-C; the disease is neoplasm.