Vascular endothelial growth factor (VEGF) is an active cytokine that modulates the angiogenesis, stimulates retinal and choroidal new vessels growth and is considered crucial for the development of choroidal neovascularization (CNV) in neovascular age-related macular degeneration (AMD) patients [3, 4]. The gene discussed is VEGFA; the disease is choroidal neovascularization.