Moreover, IGF-1 is one of the growth factors in PRP which activates tubular cell regeneration in acute renal failure probably by stimulating the release of growth hormones, which help in tissue repair [41], thus decreases tubular damage and preserves the integrity of the renal parenchyma, glomerular filtration rate, renal blood flow, and renal excretory function [42]. The gene discussed is GH1; the disease is acute kidney injury.